RAF Typhoon jets have joined forces with France's air force in a combined operation on an subterranean weapons facility in Syria used by the IS group, per a report from the UK Ministry of Defence.
The site, pinpointed through intelligence, was believed to be containing munitions and bombs, the announcement noted, and was situated in mountains just above Palmyra in central Syria.
"Our fighter planes utilized laser-guided Paveway IV weapons to target a several approach shafts leading to the site... initial indications are that the objective was successfully hit," officials stated.
There was no evidence of any civilian casualties in the strike conducted Saturday night and all the aircraft returned safely, the MoD added.
The Typhoon fighters were supported by a Voyager aerial refuelling aircraft.
Daesh - referred to as ISIS - established extremist governance over parts of Syria and Iraq until 2019.
"This strike shows British leadership, and commitment to work closely with our allies, to eradicate any re-emergence of IS and their violent and radical beliefs in the Middle East," UK Defence Secretary John Healey remarked.
RAF aircraft have carried out overwatch operations over Syria to "prevent any efforts to regroup" of the group following its defeat at the climactic battle in Baghuz in 2019, the ministry said.
"I extend gratitude to every member of British forces participating in this strike for their skill and their bravery," the Defence Secretary said. "Including them were thousands of British personnel deployed over the holidays. This action, to remove terrorist threats who endanger our security, demonstrates how UK forces are ready to step up, all year round, keeping Britain secure at home and influential overseas."
Last December, the American forces conducted what it called a "large-scale strike" on IS targets in Syria, following an assault resulted in the deaths of two US servicemembers and a civilian linguist in the Palmyra area.
The United Nations estimates Daesh still boasts roughly 5-7 thousand combatants in both countries.